Dose-Response Relationship of Oral Insulin Spray in Healthy Subjects
نویسندگان
چکیده
منابع مشابه
Dose-response relationship of oral insulin spray in healthy subjects.
OBJECTIVE To evaluate the pharmacodynamic and pharmacokinetic properties and the dose-ranging effects of an oral insulin spray in comparison with subcutaneous regular insulin. RESEARCH DESIGN AND METHODS In this randomized, five-way, cross-over study, seven healthy volunteers were assessed under euglycemic clamp and received four different doses of oral spray and one dose of subcutaneous regu...
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OBJECTIVE 1) To evaluate the effect of a single oral dose of hexyl-insulin monoconjugate 2 (HIM2) on the rate of whole-body glucose disposal (Rd) and endogenous glucose production (EGP) in healthy nondiabetic subjects, 2) to examine the reproducibility of HIM2 on glucose metabolism, and 3) to compare the results obtained with HIM2 with those using a bioequivalent dose of subcutaneous lispro ins...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2005
ISSN: 0149-5992,1935-5548
DOI: 10.2337/diacare.28.6.1353